Some of these pop more easily than others. From a skills perspective, most of them aren't difficult to obtain. The achievements that are the "hardest" just require more time. One requires 500 completed bounties for example. Yikes.
Here's a video of my last run with the game. The end boss of the final chapter falls in this one. Who knows what exciting things await in Adventure Mode? Well... I know since I did all this before on another platform... but still... WHO KNOWS?
Here's my standing after the events in the video: